The African or Cape buffalo is not believed to be closely related to the water buffalo even though they superficially resemble each other.
And unlike the water buffalo, the dangerous African buffalo has never been domesticated. Usually considered the most dangerous of the five to hunt due to its unpredictable behavior, the Cape Buffalo is nicknamed “Black Death” and the “Widowmaker”. The Cape Buffalo has few predators, namely humans and lions, and will fiercely defend itself if threatened. They are sometimes reported as killing more humans than animals. The Cape Buffalo is also the most plentiful and is not on any threatened, vulnerable, or endangered list. Their current population is 900,000, with 4 different sub-species, and 75% of the population exists in protected reserves.